Molecular Cloning and Physical Mapping of the Genome of Bombyx Mori Nuclear Polyhedrosis Virus

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Molecular cloning and physical mapping of the genome of Bombyx mori nuclear polyhedrosis virus.

A restriction fragment library which covered the entire genome of Bombyx mori nuclear polyhedrosis virus (BmNPV) was constructed using plasmid vectors. By analysis of cloned and viral DNA by double digestion with endonucleases and by hybridization techniques, a complete physical map of BmNPV was constructed for BamHI, EcoRI, HindIII, KpnI, PstI and SmaI. Five regions of repeated sequences conta...

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Cytoplasmic Polyhedrosis Virus of Bombyx mori

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Molecular characterization of Bombyx mori cytoplasmic polyhedrosis virus genome segment 4.

The complete nucleotide sequence of the genome segment 4 (S4) of Bombyx mori cytoplasmic polyhedrosis virus (BmCPV) was determined. The 3,259-nucleotide sequence contains a single long open reading frame which spans nucleotides 14 to 3187 and which is predicted to encode a protein with a molecular mass of about 130 kDa. Western blot analysis showed that S4 encodes BmCPV protein VP3, which is on...

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The p95 gene of Bombyx mori nuclear polyhedrosis virus: temporal expression and functional properties.

As part of our effort to identify baculovirus proteins acting as transcriptional regulators, we have characterized a gene, p95, of Bombyx mori nuclear polyhedrosis virus (BmNPV) that encompasses an open reading frame for a putative 95-kDa polypeptide (P95). The N-terminal half of the conceptually translated P95 contains two zinc finger-type DNA-binding motifs, and its C terminus contains a prol...

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Divergence and evolution of homologous regions of Bombyx mori nuclear polyhedrosis virus.

Homologous regions (hrs) (hr1,hr2-left,hr2-right,hr3,hr4-left,hr 4-right, and hr5) similar to those found in the Autographa californica nuclear polyhedrosis virus (AcNPV) genome were found in the Bombyx mori NPV (BmNPV) genome. The BmNPV hrs contained two to eight repeats of a homologous nucleotide sequence which were on average about 75 bp long. All of these homologous sequence repeats contain...

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ژورنال

عنوان ژورنال: Journal of General Virology

سال: 1990

ISSN: 0022-1317,1465-2099

DOI: 10.1099/0022-1317-71-8-1851